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只看该作者 90 发表于: 2006-12-03
90、HIV drugs reaching more people as AIDS Day marked
Fri Dec 1, 2006 3:39pm ET

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More Health News... Email This Article | Print This Article | Reprints [-] Text [+] By Will Dunham

WASHINGTON (Reuters) - About 1.2 million people in countries hard hit by AIDS are receiving life-extending drugs thanks to two major U.S. and international funds, double from a year ago, but many millions more need help, the funds said on Friday.

The figures were announced on World AIDS Day as activists around the world turned a spotlight on the scourge of AIDS and pleaded for more action.

South Africa unveiled a draft five-year plan to combat HIV/AIDS, the World Health Organization said prevention and treatment programs often do not reach those at highest risk, and hundreds of HIV-infected protesters gathered in New Delhi.

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More than 25 million people have died of AIDS since the incurable disease, which ravages the body's immune system, was first recognized in 1981. Almost 40 million people now live with the HIV virus that causes AIDS, with sub-Saharan Africa the hardest hit region.

The U.S. President's Emergency Plan for AIDS Relief, known as PEPFAR, and the Global Fund to Fight AIDS, Tuberculosis and Malaria said together they are bringing HIV drugs to 1.2 million people living with HIV in low- and middle-income countries.

This represents a three-fold increase since December 2003 and a doubling in the past year, the funds said. The two funds devote much of their effort in Africa.

"The pandemic of HIV-AIDS can be defeated," President Bush told reporters at the White House. "And the United States is willing to take the lead in that fight. But we can't do it alone. And so for our international partners, we appreciate what you do."

Bush said the United States is spending $15 billion over 5 years on HIV/AIDS efforts. In addition to PEPFAR, the United States is the largest contributor to the Global Fund, an international public-private partnership.   Continued...
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只看该作者 91 发表于: 2006-12-03
'A LONG WAY TO GO'

"A very rough estimate might suggest that today across the developing world 2 million people are receiving treatment while 7 million people require treatment," Richard Feachem, executive director of the Global Fund, told reporters.

"So we've gotten to something like 30 percent of the treatment addressed. And that's still a big gap and there's a long way to go," Feachem said.

Of the 2.9 million deaths from AIDS worldwide last year, 2.1 million occurred in Africa.

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South Africa is one of the worst-hit countries. Its new plan, to be finalized by March, calls for South Africa to cut in half by 2011 the annual number of new HIV infections and deliver treatment and support to 80 percent of HIV-positive children, adults and their families.

South African government officials joined community leaders and activists to unveil the plan to curb an epidemic that kills almost 1,000 South Africans a day. The plan, lacking much detail, was recognized as an important step in a country where President Thabo Mbeki's government has been criticized by AIDS activists for questioning basic tenets of AIDS science.

In Geneva, the WHO said surveillance for the HIV virus is weak in most of the world and prevention and treatment programs often fail to reach people at high risk for AIDS -- drug users, homosexuals and sex workers.

Anders Nordstrom, the agency's acting director-general, said tackling the AIDS epidemic remains one of the world's most pressing public health challenges. Only 1.6 million people, or 24 percent of the 6.8 million people worldwide who need the life-extending therapy, receive it, according to the latest joint report of UNAIDS and the WHO.

In India, which has 5.7 million infected people, hundreds of HIV-positive protesters gathered in New Delhi demanding the government provide second-line AIDS drugs free to those who have developed resistance to first-line HIV medication.   Continued...

"I know I'm dying, but if I get the drug I can live," said Umashanker Pandey, 38, an emaciated HIV-positive man from the western state of Gujarat.

In Indonesia, health and education workers planned to start handing out condoms, targeting prostitutes and customers in the capital, Jakarta.

In China, the United Nations called for overcoming stigma and discrimination in the country's vast interior.

HIV infection is rising in every region of the world, especially in east Asia and in eastern Europe/central Asia, according to the latest UNAIDS/WHO report.

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"Accountability -- the theme of this World AIDS Day -- requires every president and prime minister, every parliamentarian and politician, to decide and declare that 'AIDS stops with me,'" U.N. Secretary-General Kofi Annan said.

(Additional reporting by Stephanie Nebehay and Laura MacInnis in Geneva, Andrew Quinn in Johannesburg, Kamil Zaheer in New Delhi, and Ian Ransom and Guo Shipeng in Beijing)
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只看该作者 92 发表于: 2006-12-03
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Health Highlights: Dec. 1, 2006 Fri Dec 1, 7:02 PM ET



Here are some of the latest health and medical news developments, compiled by the editors of HealthDay:

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Experimental Ultrasound May Detect Breast Cancer


An experimental ultrasound technique may allow doctors to determine if a woman has breast cancer without having to perform a biopsy, suggest the findings of a study reported this week at a meeting of the Radiological Society of North America.


The technique, called elastography, measures how easily breast lumps compress and bounce back. The study of 80 women found that elastography was nearly 100 percent accurate in distinguishing between malignant and benign breast lumps, the Associated Press reported.


Elastography correctly identified 105 of 106 benign lumps and 17 of 17 cancerous lumps.


If the same kind of results are achieved in a larger study, the technique could spare many women the discomfort, stress, and cost of having a breast biopsy, experts said.


"There's a lot of anxiety, a lot of stress, a lot of fear involved," with a biopsy, Susan Brown, manager of health education at the Susan G. Komen Breast Cancer Foundation, told the AP. "And there's the cost of leaving work to make a second appointment. If this can be done instead of a biopsy, there would be a real cost reduction."


-----


Concerns Raised About Clotting Drug Used on U.S. Troops


The U.S. Defense Department should look into the use of the blood clotting drug Factor VII on wounded troops in     Iraq, two U.S. Senators say.


Sen. Barbara Mikulski (news, bio, voting record) (D-Md.) and Senate Minority Whip Richard Durbin (D-Ill.) called for the investigation after reports that the drug may have caused life-threatening clots, the Associated Press reported.


In a letter to Dr. William Winkenwerder Jr., Assistant Secretary of Defense for Health Affairs, Mikulski said the     Pentagon should track all patients who receive Factor VII on the battlefield in order to assess whether they are at increased risk for blood clots and other complications. As of Thursday morning, she had not received a reply.


In related news, a group of experts that specialize in hematology and blood clotting says there are "rightful concerns" about the use of the drug on the battlefield, the AP reported.


The seven scientists and doctors made the comment in an editorial they wrote for an upcoming issue of the journal Applied and Clinical Thrombosis/Hemostasis.


"Our soldiers are already in great danger and the availability of a lifesaving drug such as [Factor VII] is welcome," they wrote. "It is, however, equally important to recognize and investigate the reported adverse reactions with its use to avoid additional risk to these Army personnel."


Factor VII was originally designed to treat patients with rare forms of hemophilia. The U.S. military says the drug gives front-line doctors a way to control potentially fatal bleeding in wounded troops, the AP said.


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U.S. Workers Prefer Traditional Health Plans

A survey released Friday shows that Americans with employer-sponsored health coverage are more likely to sign up for traditional plans instead of consumer-directed products, which have been promoted as a way to reduce healthcare costs.

When given a choice of at least two plans, 55 percent of workers chose a preferred provider organization (PPO), 40 percent selected a health maintenance organization (HMO), and 19 percent went with a consumer-directed plan, the Associated Press reported.

The survey by the Washington, D.C.-based Center for Studying Health System Change also found that 39 percent of the 2.7 million people enrolled in employer-sponsored consumer directed health plans in 2006 were not offered other choices.

Consumer-directed health plans feature high deductibles and tax-advantaged savings accounts. This type of plan is supposed to help reduce health care costs by making patients more accountable for their health spending decisions, the AP reported.

However, the survey findings suggest that Americans don't necessarily want that kind of responsibility, said Jon Gabel, one of the study authors and vice president of the Center for Studying Health System Change.

"Most Americans are risk-averse. They don't like making financial decisions," Gabel told the AP.

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Young Adults Who Cook Eat Healthier

Young American adults who buy their own food and prepare meals at home eat fast food less often, consume more fruits and vegetables, and eat a more healthy diet overall than those who don't take part in the planning and cooking of their meals, according to University of Minnesota researchers who surveyed more than 1,500 people, ages 18 to 23.

The survey found that 31 percent of young adults who were heavily involved in meal preparation ate five servings of fruits and vegetables a day, compared with 3 percent of those with little involvement in meal preparation.

But even among those who did take part in buying and preparing food, many did not meet recommended dietary guidelines.

"Cooking skills, money to buy food and time available for food preparation were perceived as inadequate by approximately one-fifth to more than one-third of the sample," the study authors wrote. "To improve dietary intake, interventions among young adults should teach skills for preparing quick and healthful meals."

The study appears in the December issue of the Journal of the American Dietetic Association.

Another study in the same issue of the journal found that drinking a large sweetened beverage, such as soda, at a meal can increase the total amount of calories consumed by more than 25 percent.

The University of Pennsylvania study of 33 people found that drinking an 18-ounce soda at a meal increased calorie intake by 10 percent for women and 26 percent for men. Drinking unsweetened beverages or water at meals can help reduce calorie intake, the researchers concluded.

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Family Cancer History Boosts Black Men's Prostate Cancer Risk

Black American men with siblings who've had prostate or breast cancer appear to have an increased risk for prostate cancer, according to a study by researchers at the University of Michigan (U-M).

The findings, published in the November issue of the journal Urology, support previous research that found an increased risk of prostate cancer in men whose brothers had the disease.

The study included 121 prostate cancer patients and 179 men who did not have the disease. The prostate cancer patients were 4.8 times more likely to report having a brother diagnosed with prostate cancer and about 4 times more likely to report having a sister diagnosed with breast cancer.

"Previous studies have suggested having a brother with prostate cancer confers higher risk than another relative, such as a father or son. But this is the first time a link has been shown between sisters with breast cancer and prostate cancer risk among African-American men," study lead author Jennifer Beebe-Dimmer, assistant research scientist and lecturer, department of epidemiology, U-M School of Public Health, said in a prepared statement.
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只看该作者 93 发表于: 2006-12-03
92、Primary Navigation
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Health Tip: Fish is Good for Your Heart Fri Dec 1, 11:47 PM ET



(HealthDay News) -- Adding fish to your diet can help reduce your risk of a heart attack. The     American Heart Association recommends eating at least two servings a week of fatty fish, high in omega-3 fatty acids.

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Fish that are particularly high in these heart-healthy compounds include mackeral, salmon, lake trout, sardines, herring and albacore tuna.


In studies, omega-3 fatty acids have been shown to slightly reduce blood pressure, reduce plaque buildup in the arteries, and lower cholesterol levels. They can also reduce the risk of potentially dangerous heartbeat irregularities.
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只看该作者 94 发表于: 2006-12-03
93、Primary Navigation
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Health Tip: Take ADHD Medication as Prescribed Fri Dec 1, 11:47 PM ET



(HealthDay News) -- Medications used to treat attention-deficit hyperactivity disorder (ADHD) can be very effective if taken as prescribed by your doctor.

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But these medicines can trigger serious side effects if taken by a person who does not have ADHD, or if you take more than what is prescribed.


Here are potential side effects of overdosing on an ADHD medication, courtesy of the Nemours Foundation:

Tremors and shaking.
Extremely high blood pressure and increased heart rate.
Rapid breathing.
Delusions, confusion, paranoia or hallucinations.
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只看该作者 95 发表于: 2006-12-03
94、Health Tip: Take ADHD Medication as Prescribed Fri Dec 1, 11:47 PM ET



(HealthDay News) -- Medications used to treat attention-deficit hyperactivity disorder (ADHD) can be very effective if taken as prescribed by your doctor.

ADVERTISEMENT

But these medicines can trigger serious side effects if taken by a person who does not have ADHD, or if you take more than what is prescribed.


Here are potential side effects of overdosing on an ADHD medication, courtesy of the Nemours Foundation:

Tremors and shaking.
Extremely high blood pressure and increased heart rate.
Rapid breathing.
Delusions, confusion, paranoia or hallucinations.
级别: 管理员
只看该作者 96 发表于: 2006-12-03
95、Primary Navigation
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Health Tip: Warning Sign of a Major Stroke Thu Nov 30, 11:47 PM ET



(HealthDay News) -- Transient ischemic attacks (TIAs) are small strokes that often precede a major stroke.

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While most strokes aren't preceded by TIAs, if you do have a TIA, you should learn to recognize its warning signs. This can help you and your doctor prevent a major episode that can cause significant and permanent brain damage, the     American Heart Association says.


Symptoms of a TIA are similar to those of a full-blown stroke, but they typically last for only a short time. These warning signs can include dizziness, loss of coordination or balance, and numbness or weakness on only one side. Some people may also have difficulty speaking, vision problems, or an unexplained severe headache.


If you have these symptoms, even briefly, see a doctor immediately.
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只看该作者 97 发表于: 2006-12-03
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Health Tip: Your Child Needs Regular Eye Exams Thu Nov 30, 11:47 PM ET



(HealthDay News) -- Regular eye checkups are important, especially for children, the American Optometric Association says.

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The newborn checkup at the hospital isn't enough, the group warns. By age 6 months, the association recommends that all children undergo a thorough eye exam.


If your child has a healthy prognosis from her eye exam, the AOA says she probably won't need another checkup until about age 3, and again before she starts school. Preventive checkups can help diagnose conditions including vision loss, lazy eye, or crossed eyes.


You should see an eye doctor at once if you notice abnormalities in your child's vision, says the AOA. You should also have regular optometric visits if your child has risk factors for eye disease, including low birth weight or a mother who had a sexually transmitted disease, rubella, or abused drugs or alcohol during pregnancy.
级别: 管理员
只看该作者 98 发表于: 2006-12-03
97、Primary Navigation
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Health Tip: Your Child Needs Regular Eye Exams Thu Nov 30, 11:47 PM ET



(HealthDay News) -- Regular eye checkups are important, especially for children, the American Optometric Association says.

ADVERTISEMENT

The newborn checkup at the hospital isn't enough, the group warns. By age 6 months, the association recommends that all children undergo a thorough eye exam.


If your child has a healthy prognosis from her eye exam, the AOA says she probably won't need another checkup until about age 3, and again before she starts school. Preventive checkups can help diagnose conditions including vision loss, lazy eye, or crossed eyes.


You should see an eye doctor at once if you notice abnormalities in your child's vision, says the AOA. You should also have regular optometric visits if your child has risk factors for eye disease, including low birth weight or a mother who had a sexually transmitted disease, rubella, or abused drugs or alcohol during pregnancy.
级别: 管理员
只看该作者 99 发表于: 2006-12-03
98、Primary Navigation
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Herpes study put pregnant women at risk By ANDREW BRIDGES, Associated Press Writer
Fri Dec 1, 8:03 PM ET



WASHINGTON - Dozens of poor and minority pregnant women were put at risk when they were given dummy pills instead of a drug believed to prevent outbreaks of genital herpes, consumer watchdogs charged Friday.

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The researchers defended their work, saying in part the study was to assess the uncertain risks of the drug to the women's fetuses.

In the study, researchers at Parkland Hospital in Dallas gave 170 pregnant women the drug valacyclovir to see if the drug would reduce herpes outbreaks at birth. The virus can be fatal to newborns if infected during delivery. An additional 168 women from the largely indigent population the hospital serves were given dummy pills. More of those women went on to have Caesarean sections than did those given valacyclovir, which the body breaks down to form the herpes drug acyclovir.

Since the researchers had published a study midway through the clinical trial that concluded giving women acyclovir could reduce the C-section rate, critics allege they needlessly put half the women at risk by not giving them the drug instead of dummy pills.

"What I don't understand is how you can do a research study and conclude that a drug is effective and then stare a bunch of pregnant women in the face and withhold the very drug you've just recommended," said Dr. Peter Lurie, of the watchdog group Public Citizen.

Lurie and two other doctors leveled their criticism in a letter appearing this month in the journal Obstetrics & Gynecology. The journal published both the 2003 study by the researchers suggesting a benefit to treating women with acyclovir, as well a July 2006 study that concluded valacyclovir significantly reduced the outbreaks that lead to C-sections.

A doctor involved in the studies, Dr. George Wendel, would not comment specifically on allegations that poor women were taken advantage of. In an interview, he said the study was designed and conducted "according to good research practices" and approved by the hospital's ethics review board.

Wendel and his colleagues also published a rebuttal in the journal, saying in part that the study balanced the risks and benefits of valacyclovir to both the mothers and their fetuses.

Clinical trials of new drugs typically compare them with dummy pills ― unless there already is an effective treatment available.

Wendel also said their 2003 work didn't conclude acyclovir should be recommended, only that more research was needed.

Since 1999, the American College of Obstetrics and Gynecology, publisher of the journal, has recommended acyclovir treatment be considered late in pregnancy for women who suffer their first genital herpes outbreak while pregnant.

Acyclovir is widely available in generic form. Valacyclovir is sold as Valtrex by GlaxoSmithKline, which sponsored the 2006 study.

___

On the Net:

American College of Obstetrics and Gynecology: http://www.acog.org/

Public Citizen: http://www.citizen.org/
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